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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREPL
All Species:
22.73
Human Site:
Y231
Identified Species:
45.45
UniProt:
Q4J6C6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4J6C6
NP_001035844.1
727
83927
Y231
N
L
R
C
H
D
V
Y
R
A
T
F
G
D
N
Chimpanzee
Pan troglodytes
XP_001144400
727
83999
Y231
N
L
R
C
H
D
V
Y
R
A
T
F
G
D
N
Rhesus Macaque
Macaca mulatta
XP_001111959
727
83985
Y231
N
L
R
C
H
D
V
Y
R
A
T
F
G
D
N
Dog
Lupus familis
XP_531803
727
83861
Y231
N
L
R
C
H
D
V
Y
R
A
T
F
G
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C167
725
83176
Y229
N
L
R
C
H
D
V
Y
R
A
T
F
G
D
N
Rat
Rattus norvegicus
Q5HZA6
726
83463
Y230
N
L
R
C
H
D
V
Y
R
A
T
F
G
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521562
342
37329
Chicken
Gallus gallus
Q5ZKL5
732
84295
F245
N
L
K
C
Q
N
V
F
M
T
T
F
T
N
E
Frog
Xenopus laevis
Q32N48
707
80150
A208
V
Q
C
R
Q
V
F
A
T
D
F
S
D
A
N
Zebra Danio
Brachydanio rerio
NP_001139088
692
78210
F213
E
E
K
D
P
K
F
F
V
E
V
S
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780381
720
80994
V210
S
Q
Q
G
D
E
L
V
F
E
E
M
D
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151599
784
87028
F250
T
L
R
P
N
Q
V
F
C
K
K
L
Q
S
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
96.1
N.A.
90.9
90.3
N.A.
26.5
47.5
42
37.9
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
99.7
99.5
98.3
N.A.
95
94.7
N.A.
34.5
66.6
61.4
54.8
N.A.
N.A.
N.A.
N.A.
51.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
40
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
66.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
50
0
0
0
9
0
% A
% Cys:
0
0
9
59
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
50
0
0
0
9
0
0
17
50
9
% D
% Glu:
9
9
0
0
0
9
0
0
0
17
9
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
17
25
9
0
9
59
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
50
0
0
% G
% His:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
17
0
0
9
0
0
0
9
9
0
0
0
0
% K
% Leu:
0
67
0
0
0
0
9
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% M
% Asn:
59
0
0
0
9
9
0
0
0
0
0
0
0
9
59
% N
% Pro:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
9
0
17
9
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
59
9
0
0
0
0
50
0
0
0
9
0
17
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
0
17
0
17
0
% S
% Thr:
9
0
0
0
0
0
0
0
9
9
59
0
9
0
0
% T
% Val:
9
0
0
0
0
9
67
9
9
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _